Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10287152 | 0.89 | HDAC6 (0.34) | HDAC6HDAC1HDAC8HDAC4 | |
| SCHEMBL808234 | 0.88 | HDAC6 (0.34) | HDAC6HDAC1HDAC8HDAC4 | |
| SCHEMBL10287197 | 0.87 | CPT2 (0.33) | ALOX5AP | |
| SCHEMBL808236 | 0.83 | TSHR (0.39) | HDAC6HDAC1HDAC8 | |
| SCHEMBL10286912 | 0.81 | GABRA1 (0.36) | HDAC6HDAC1HDAC8HDAC4 | |
| SCHEMBL808237 | 0.81 | HIF1A (0.39) | — | |
| SCHEMBL808161 | 0.78 | HDAC4 (0.32) | HDAC6HDAC8HDAC4 | |
| SCHEMBL807937 | 0.78 | GABRA5 (0.34) | — | |
| SCHEMBL808333 | 0.78 | NPC1 (0.37) | HDAC6HDAC1KMT2AHDAC8HDAC4 | |
| SCHEMBL10287297 | 0.77 | ACACB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |