Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 3/20 | 0.36 |
| ▸ | EDNRA | P25101 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8082083 | 0.87 | TDP1 (0.42) | MEN1KMT2APARP1EDNRBEDNRA | |
| SCHEMBL8085156 | 0.86 | ALOX5 (0.44) | MEN1KMT2ADYRK3CSNK2A2CSNK2B | |
| SCHEMBL8085195 | 0.84 | MAPT (0.45) | MEN1KMT2AEDNRBEDNRAALDH1A1 | |
| SCHEMBL8085152 | 0.81 | ALOX5 (0.38) | MEN1KMT2AEDNRBEDNRAALDH1A1 | |
| SCHEMBL8081635 | 0.80 | ALOX5 (0.40) | MEN1KMT2AEDNRAALOX5 | |
| SCHEMBL8085138 | 0.79 | ALOX5 (0.46) | MEN1KMT2APARP1EDNRBEDNRA | |
| SCHEMBL8082065 | 0.78 | ALOX5 (0.45) | MEN1KMT2AALOX5 | |
| SCHEMBL8467071 | 0.78 | EDNRB (0.34) | DYRK3CSNK2A2CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL8082003 | 0.74 | TDP1 (0.44) | MEN1KMT2AALDH1A1ALOX5MAPT | |
| SCHEMBL8080564 | 0.74 | CDK2 (0.41) | MEN1KMT2AEDNRBEDNRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030967-A | AND/OR LIKE NEUROTROPHIC FACTOR (FOR EXAMPLE, NERVE GROWTH FACTOR (NGF), BRAIN-DERIVED NEUROTROPHIC FACTOR, NEUROTROPHIN-3, AND GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR)-LIKE ACTIVITY; OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-02-29 | — | — | US | disclosed |