Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808237 | 0.89 | HIF1A (0.39) | USP30GABRA1MLLT1 | |
| SCHEMBL10287152 | 0.88 | HDAC6 (0.34) | HDAC1HDAC6NPC1RAB9AHDAC8 | |
| SCHEMBL808234 | 0.87 | HDAC6 (0.34) | HDAC1HDAC6NPC1RAB9AHDAC8 | |
| SCHEMBL10287197 | 0.85 | CPT2 (0.33) | TSHRACKR3NPC1RAB9AKDM1A | |
| SCHEMBL10286912 | 0.85 | GABRA1 (0.36) | HDAC1HDAC6GABRA1HDAC8TGFBR1 | |
| SCHEMBL808241 | 0.83 | HDAC6 (0.33) | HDAC1HDAC6HDAC8 | |
| SCHEMBL10287297 | 0.79 | ACACB (0.36) | — | |
| SCHEMBL807936 | 0.79 | KCNH2 (0.32) | USP30 | |
| SCHEMBL808331 | 0.79 | KCNH2 (0.32) | TSHRUSP30S1PR1 | |
| SCHEMBL808333 | 0.79 | NPC1 (0.37) | HDAC1HDAC6NPC1RAB9AHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |