Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808331 | 0.98 | KCNH2 (0.32) | KCNH2MCHR1SCN9AGABRA5USP30 | |
| SCHEMBL807787 | 0.94 | SCN9A (0.37) | SCN9AGABRA5 | |
| SCHEMBL808238 | 0.90 | TDO2 (0.36) | KCNH2MCHR1USP30 | |
| SCHEMBL10287297 | 0.87 | ACACB (0.36) | GABRA5 | |
| SCHEMBL10287197 | 0.85 | CPT2 (0.33) | KCNH2MCHR1 | |
| SCHEMBL807937 | 0.83 | GABRA5 (0.34) | GABRA5 | |
| SCHEMBL808332 | 0.82 | GABRA5 (0.34) | KCNH2SCN9AGABRA5 | |
| SCHEMBL10287152 | 0.81 | HDAC6 (0.34) | — | |
| SCHEMBL808159 | 0.80 | ACHE (0.31) | — | |
| SCHEMBL808234 | 0.80 | HDAC6 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |