Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | NAPEPLD | Q6IQ20 | 10/20 | 0.35 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808236 | 0.89 | TSHR (0.39) | USP30GABRA1MLLT1 | |
| SCHEMBL10286912 | 0.87 | GABRA1 (0.36) | HIF1AGABRA1NAPEPLD | |
| SCHEMBL10287152 | 0.86 | HDAC6 (0.34) | — | |
| SCHEMBL808234 | 0.85 | HDAC6 (0.34) | — | |
| SCHEMBL10287197 | 0.83 | CPT2 (0.33) | — | |
| SCHEMBL10287297 | 0.82 | ACACB (0.36) | — | |
| SCHEMBL808241 | 0.81 | HDAC6 (0.33) | — | |
| SCHEMBL808159 | 0.80 | ACHE (0.31) | — | |
| SCHEMBL807936 | 0.78 | KCNH2 (0.32) | USP30 | |
| SCHEMBL808331 | 0.77 | KCNH2 (0.32) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |