Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808343 | 0.89 | SCD (0.34) | SCDOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL808024 | 0.85 | TSHR (0.37) | SIGMAR1 | |
| SCHEMBL808032 | 0.81 | DHFR (0.34) | SCDSCD5SIGMAR1 | |
| SCHEMBL808232 | 0.80 | CNR2 (0.32) | SIGMAR1 | |
| SCHEMBL808046 | 0.76 | GAA (0.31) | — | |
| SCHEMBL808039 | 0.75 | CKS1B (0.33) | — | |
| SCHEMBL808026 | 0.72 | — | — | |
| SCHEMBL10287187 | 0.71 | ALDH1A1 (0.45) | — | |
| SCHEMBL807906 | 0.71 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL808211 | 0.69 | RPS6KA2 (0.33) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |