Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3799753 | 0.81 | MEN1 (0.50) | HPGDCA2CA9CA14HTT | |
| SCHEMBL8091468 | 0.81 | PLK1 (0.36) | HPGDCA1CA2CES2CES1 | |
| SCHEMBL8589340 | 0.77 | BLM (0.37) | CYP2C19 | |
| SCHEMBL8587462 | 0.77 | MMP2 (0.33) | MMP2LMNACYP3A4CYP2C19 | |
| SCHEMBL3219196 | 0.76 | SRC (0.60) | ACP3HPGDCA1CA2CA12 | |
| SCHEMBL3246349 | 0.76 | CES2 (0.53) | ACP3HPGDCA1CA2CA12 | |
| SCHEMBL10935883 | 0.76 | CA1 (0.48) | ACP3HPGDCA1CA2CA12 | |
| SCHEMBL8587107 | 0.75 | SRC (0.42) | HPGDCA1CA2CA12CA9 | |
| Hydrochloric Acid SCHEMBL28893937 | 0.74 | SRC (0.58) | ACP3HPGDCA1CA2CA12 | |
| SCHEMBL28074568 | 0.74 | CYP2C19 (0.60) | ACP3HPGDCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057488-A1 | INTERLEUKIN-6 PRODUCTION INHIBITORS | TORAY INDUSTRIES, INC. (JP) | 2000-12-06 | — | — | EP | claimed |
| EP-1057488-A1 | INTERLEUKIN-6 PRODUCTION INHIBITORS | TORAY INDUSTRIES, INC. (JP) | 2000-12-06 | — | — | EP | disclosed |