Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 4/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091468 | 0.83 | PLK1 (0.36) | SMN1; SMN2BLMCYP2C19LMNAPOLB | |
| SCHEMBL8589340 | 0.79 | BLM (0.37) | SMN1; SMN2BLMCYP2C19GAANPC1 | |
| SCHEMBL8083418 | 0.77 | ACP3 (0.42) | MMP2CYP2C19LMNACYP3A4 | |
| SCHEMBL8587107 | 0.77 | SRC (0.42) | MMP2SMN1; SMN2LMNAPOLBSRC | |
| SCHEMBL8589711 | 0.75 | CA2 (0.40) | SMN1; SMN2BLMCYP2C19 | |
| SCHEMBL3799753 | 0.74 | MEN1 (0.50) | MMP2MMP8MMP14SMN1; SMN2CYP2C19 | |
| SCHEMBL8589186 | 0.73 | SLC6A4 (0.39) | SMN1; SMN2BLMCYP2C19LMNARAB9A | |
| SCHEMBL8589072 | 0.69 | — | — | |
| SCHEMBL8586119 | 0.68 | ALDH1A1 (0.55) | THRBCYP3A4TSHR | |
| SCHEMBL8589347 | 0.68 | MMP2 (0.66) | MMP2MMP8MMP14SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594857-B1 | METHANEDIPHOSPHONIC ACID DERIVATIVE, PRODUCTION THEREOF AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 1998-04-29 | — | — | EP | disclosed |
| US-5683992-A | TREATMENT OF RHEUMATISM, BONE DISORDERS, ANTIINFLAMMATORY, SUPPRESSION OF INTERLEUKIN-1, ANTIOXIDANT, TREATMENT OF AUTOIMMUNE DISEASES | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |
| US-5527940-A | SUPPRESSES INTERLEUKIN-1 AND BONE DESTRUCTION DURING OSTEOPOROSIS; ANTIINFLAMMATORY AGENTS | TORAY INDUSTRIES, INC. (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0594857-A1 | METHANEDIPHOSPHONIC ACID DERIVATIVE, PRODUCTION THEREOF AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1994-05-04 | — | — | EP | disclosed |