Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808036 | 0.90 | POLB (0.34) | POLBMAPK1MAPTSCN9AALDH1A1 | |
| SCHEMBL808348 | 0.79 | MAPT (0.37) | POLBMAPK1MAPTALDH1A1RECQL | |
| SCHEMBL808332 | 0.79 | GABRA5 (0.34) | POLBMAPK1SCN9ANPSR1 | |
| SCHEMBL10287198 | 0.74 | HDAC6 (0.34) | SCN9A | |
| SCHEMBL10287123 | 0.74 | POLB (0.41) | POLBMAPK1MAPTSCN9AALDH1A1 | |
| SCHEMBL808161 | 0.73 | HDAC4 (0.32) | — | |
| SCHEMBL807937 | 0.73 | GABRA5 (0.34) | — | |
| SCHEMBL795199 | 0.71 | HDAC1 (0.34) | SCN9AALDH1A1RECQLTRPV3NPSR1 | |
| SCHEMBL808240 | 0.70 | HDAC6 (0.35) | ALDH1A1 | |
| SCHEMBL10286912 | 0.70 | GABRA1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |