Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098731 | 0.84 | CYP1A2 (0.34) | HTTKMT2ACFTR | |
| SCHEMBL8091901 | 0.84 | LMNA (0.40) | ARALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL8083938 | 0.84 | RHOC (0.35) | ALDH1A1KDM4EKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL8083649 | 0.80 | S1PR1 (0.37) | KMT2AS1PR1HDAC3HDAC1HDAC2 | |
| SCHEMBL8604509 | 0.79 | L3MBTL1 (0.41) | ARKDM4E | |
| SCHEMBL8602899 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HSD17B10KDM4EKMT2AS1PR1 | |
| SCHEMBL8098268 | 0.78 | SMN1; SMN2 (0.35) | ARKDM4EKMT2ASMN1; SMN2HDAC3 | |
| SCHEMBL8098784 | 0.75 | NPSR1 (0.39) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL8083711 | 0.73 | FFAR4 (0.36) | ARALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL8118357 | 0.73 | NR2E1 (0.35) | CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136805-A | Quinoxaline dione derivatives, their production and their use in medicaments | SCNERING AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |
| EP-0828746-A1 | NOVEL QUINOXALINE DIONE DERIVATIVES, THEIR PRODUCTION AND THEIR USE IN MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037500-A1 | NOVEL QUINOXALINE DIONE DERIVATIVES, THEIR PRODUCTION AND THEIR USE IN MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-11-28 | — | — | WO | disclosed |