Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181084 | 0.84 | CFTR (0.51) | CFTRWDR5SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8083711 | 0.81 | FFAR4 (0.36) | AKR1C3AKR1C2AKR1C4AKR1C1AKR1B10 | |
| SCHEMBL8098272 | 0.79 | UBE2M (0.34) | DHODHEPHX2HPGDPPARG | |
| SCHEMBL8083940 | 0.77 | RHOC (0.36) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL8098790 | 0.76 | NPSR1 (0.36) | DHODHKDM4EALDH1A1MAPT | |
| SCHEMBL8090776 | 0.76 | PTGER4 (0.38) | EPHX2MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL8083652 | 0.75 | PPARG (0.36) | MEN1KMT2AMAPTPPARG | |
| SCHEMBL8342163 | 0.75 | SERPINE1 (0.37) | TP53NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8345101 | 0.74 | ALDH1A1 (0.41) | TP53SMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL8098738 | 0.73 | CYP1A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136805-A | Quinoxaline dione derivatives, their production and their use in medicaments | SCNERING AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |