Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370837 | 0.86 | NPC1 (0.37) | POLBAPEX1NPC1GAACUL4A | |
| SCHEMBL8084592 | 0.83 | CUL4A (0.46) | POLBAPEX1NPC1GAACUL4A | |
| SCHEMBL17466053 | 0.80 | KDM4E (0.42) | POLBAPEX1NPC1GAAMAPT | |
| SCHEMBL8604258 | 0.79 | CUL4A (0.49) | NPC1GAACUL4AMAPTRAB9A | |
| SCHEMBL8602332 | 0.79 | RORC (0.35) | NPC1GAACUL4AMAPTRAB9A | |
| SCHEMBL1984953 | 0.79 | ELANE (0.43) | ELANEGAACUL4ACA2CA12 | |
| SCHEMBL30739992 | 0.79 | ELANE (0.43) | ELANEGAACUL4ACA2CA12 | |
| SCHEMBL8598548 | 0.79 | LMNA (0.46) | POLBMTNR1AMTNR1BNPC1MAPT | |
| SCHEMBL8601381 | 0.78 | PPOX (0.40) | POLBAPEX1NPC1GAAAPP | |
| SCHEMBL27298534 | 0.78 | NPC1 (0.36) | POLBAPEX1NPC1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |