Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088675 | 0.89 | RECQL (0.44) | HTTTDP1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8077334 | 0.86 | ALDH1A1 (0.38) | TDP1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8076907 | 0.85 | TDP1 (0.37) | HTTTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8084426 | 0.85 | ALDH1A1 (0.36) | TDP1ALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL8077303 | 0.85 | ALDH1A1 (0.36) | TDP1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8090492 | 0.83 | KDM4E (0.36) | HTTTDP1MAPTALDH1A1KMT2A | |
| SCHEMBL8085346 | 0.82 | ALDH1A1 (0.38) | TDP1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8090777 | 0.82 | PDE4A (0.38) | KMT2AMEN1 | |
| SCHEMBL8085103 | 0.81 | CFTR (0.41) | HTTMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8088445 | 0.80 | ADORA3 (0.41) | ADORA3ADORA2AHTTTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153627-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-28 | — | — | US | disclosed |
| US-6040308-A | Chroman derivatives | MERCK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5013853-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-05-07 | — | — | US | disclosed |