Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | ESR1 | P03372 | 2/20 | 0.61 |
| ▸ | CA7 | P43166 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.61 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL572 | 0.87 | KMT2A (0.58) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL8585196 | 0.85 | ALDH1A1 (0.53) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL11515591 | 0.85 | TSHR (0.66) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL27978253 | 0.85 | CA12 (0.49) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL23149729 | 0.84 | PARP10 (0.53) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL13634 | 0.84 | KMT2A (0.66) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL1374042 | 0.84 | HSD17B3 (0.61) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL13516645 | 0.84 | ALDH1A1 (0.55) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL8600414 | 0.84 | LMNA (0.62) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL314260 | 0.84 | KMT2A (0.54) | ALDH1A1KMT2AKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55136251-A | — | — | None | — | — | JP | disclosed |
| CN-108658991-B | Preparation method and application of 3, 5-disubstituted methylpyrazolo [1,5-a ] pyrimidine-7-phenolate analogue and derivative | 辽宁利锋科技开发有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-109651325-B | Synthetic method of naphtho [1,2,3-de ] benzopyran-2, 7-diketone compound | 青岛理工大学 | 2022-04-08 | — | — | CN | disclosed |
| US-20210094954-A1 | PREPARATION METHODS AND APPLICATIONS OF 3,5-DISUBSTITUTED METHYLPYRAZOLO[1,5-A]PYRIMIDINE-7-HYDROXYLIC SALTS | XU LIFENG (US) | 2021-04-01 | — | — | US | disclosed |
| US-7364834-B2 | Functional polymer | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2008-04-29 | — | — | US | disclosed |
| US-7364834-B2 | Functional polymer | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2008-04-29 | — | — | US | disclosed |
| US-6140310-A | ADMINISTERING AN EFFECTIVE AMOUNT OF PHOSPHORUS PRODRUG IN A MAMMAL FOR TREATING A VIRAL INFECTION | DRUG INNOVATION & DESIGN, INC. (US) | 2000-10-31 | — | — | US | disclosed |
| US-5789608-A | LIPID SOLUBLE; DIFFUSE INTO CELLS AND TISSUE; VIRICIDES, ANTICANCER AGENTS | DRUG INNOVATION AND DESIGN, INC. (US) | 1998-08-04 | — | — | US | disclosed |
| US-5627165-A | ANTIVIRAL AND ANTILEUKEMIA AGENTS | DRUG INNOVATION & DESIGN, INC. (US) | 1997-05-06 | — | — | US | disclosed |
| EP-0533833-B1 | PHOSPHOROUS PRODUGS | GLAZIER ARNOLD (US) | 1995-12-20 | — | — | EP | disclosed |
| US-5274162-A | Antineoplastic drugs with bipolar toxification/detoxification functionalities | GLAZIER ARNOLD (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0533833-A1 | PHOSPHOROUS PRODRUGS. | GLAZIER ARNOLD (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991019721-A1 | PHOSPHOROUS PRODUGS | GLAZIER ARNOLD (US) | 1991-12-26 | — | — | WO | disclosed |
| JP-S55136251-A | NOVEL KETO ESTER COMPOUND | ORIENTAL SHASHIN KOGYO KK | 1980-10-23 | — | — | JP | disclosed |
| US-4176196-A | Hypoglycemic arylcyclohexane acetic acids | PFIZER INC. (US) | 1979-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094954-A1 | PREPARATION METHODS AND APPLICATIONS OF 3,5-DISUBSTITUTED METHYLPYRAZOLO[1,5-A]PYRIMIDINE-7-HYDROXYLIC SALTS | DHPS, NUDT1, DPYD | CA12 3570/4885CA1 2461/4885CA2 693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.