Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 5/20 | 0.45 |
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616194 | 0.90 | CA2 (0.45) | ANPEPCA12CA1CA7CA14 | |
| SCHEMBL7309512 | 0.89 | CA12 (0.50) | CA12CA1CA7CA14ATM | |
| SCHEMBL8617454 | 0.88 | CA2 (0.51) | CTSSCTSKCA2KMT2ASYK | |
| SCHEMBL8617778 | 0.87 | CTSS (0.56) | ATMCTSSCTSKKMT2ACTSL | |
| SCHEMBL8086793 | 0.83 | KMT2A (0.52) | CTSSCTSKCA2KMT2ASYK | |
| SCHEMBL8075350 | 0.83 | KMT2A (0.52) | CTSSCTSKCA2KMT2ASYK | |
| SCHEMBL8620934 | 0.83 | CTSD (0.55) | ATMCTSSCTSKKMT2ACTSL | |
| SCHEMBL8620133 | 0.83 | CTSS (0.55) | ATMCTSSCTSKKMT2ACTSL | |
| SCHEMBL8613804 | 0.81 | CTSS (0.50) | ATMCTSSCTSKKMT2ACTSL | |
| SCHEMBL8549092 | 0.81 | CTSS (0.64) | ANPEPATMCTSSCTSKCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |