Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085199 | 0.81 | ABCC9 (0.42) | ABCC9NPC1RAB9A | |
| SCHEMBL7333922 | 0.81 | ABCC9 (0.40) | ABCC9 | |
| SCHEMBL7331673 | 0.80 | ABCC9 (0.39) | ABCC9KDM4E | |
| SCHEMBL8085013 | 0.80 | ABCC9 (0.41) | ABCC9HTTPKMKDM4EMAPT | |
| SCHEMBL7274240 | 0.79 | ABCC9 (0.62) | ABCC9ALOX15KDM4E | |
| SCHEMBL9589058 | 0.77 | ABCC9 (0.48) | ABCC9 | |
| SCHEMBL9589053 | 0.77 | ABCC9 (0.48) | ABCC9 | |
| SCHEMBL9589063 | 0.77 | ABCC9 (0.48) | ABCC9 | |
| SCHEMBL9524371 | 0.72 | KDM4E (0.42) | ALOX5ALOX15HTTPKMKDM4E | |
| SCHEMBL10956358 | 0.71 | ALOX5 (0.45) | ABCC9ALOX5TRPA1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153627-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-28 | — | — | US | disclosed |
| US-6040308-A | Chroman derivatives | MERCK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5387587-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |