Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 9/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.32 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | FURIN | P09958 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9589058 | 1.00 | ABCC9 (0.48) | ABCC9IDO1KCNE1KCNQ1PTGS2 | |
| SCHEMBL9589063 | 1.00 | ABCC9 (0.48) | ABCC9IDO1KCNE1KCNQ1PTGS2 | |
| SCHEMBL8085199 | 0.81 | ABCC9 (0.42) | ABCC9KCNE1KCNQ1ABCB1 | |
| SCHEMBL7274240 | 0.78 | ABCC9 (0.62) | ABCC9ABCB1 | |
| SCHEMBL8085013 | 0.78 | ABCC9 (0.41) | ABCC9TDP1 | |
| SCHEMBL8088486 | 0.77 | ABCC9 (0.42) | ABCC9 | |
| SCHEMBL10266075 | 0.73 | ABCC9 (0.49) | ABCC9KCNE1KCNQ1 | |
| SCHEMBL482632 | 0.73 | ABCC9 (0.49) | ABCC9KCNE1KCNQ1 | |
| SCHEMBL7331034 | 0.71 | ABCC9 (0.56) | ABCC9KCNE1KCNQ1ABCB1 | |
| SCHEMBL9042201 | 0.70 | ABCC9 (0.49) | ABCC9KCNE1KCNQ1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254557-A | Administering for reversible airways obstruction and asthma | BEECHAM GROUP P.L.C. (GB) | 1993-10-19 | — | — | US | disclosed |
| EP-0373204-A1 | NOVEL COMPOUNDS AND TREATMENT | BEECHAM GROUP PLC (GB) | 1990-06-20 | — | — | EP | disclosed |
| WO-1989010925-A1 | NOVEL COMPOUNDS AND TREATMENT | BEECHAM GROUP PLC (GB) | 1989-11-16 | — | — | WO | disclosed |