Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAD | P27708 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8142588 | 1.00 | CAD (0.39) | CADATMITGB3ITGAVGAA | |
| SCHEMBL8088672 | 0.85 | ALDH1A1 (0.37) | ITGB3SMN1; SMN2MAPK1LMNANOD1 | |
| SCHEMBL9830204 | 0.84 | ATM (0.40) | CADATMITGB3ITGAVGAA | |
| SCHEMBL28009494 | 0.82 | TGFBR1 (0.53) | CADATMITGB3ITGAVGAA | |
| SCHEMBL17224588 | 0.82 | TGFBR1 (0.53) | CADATMITGB3ITGAVGAA | |
| SCHEMBL28710585 | 0.82 | TGFBR1 (0.53) | CADATMITGB3ITGAVGAA | |
| SCHEMBL30202144 | 0.82 | EPHX1 (0.43) | ITGB3SMN1; SMN2NOD1L3MBTL1ALDH1A1 | |
| SCHEMBL9716671 | 0.82 | FOLH1 (0.47) | ITGB3NOD1CYP1A2FOLH1 | |
| SCHEMBL9716665 | 0.82 | FOLH1 (0.47) | ITGB3NOD1CYP1A2FOLH1 | |
| SCHEMBL7368743 | 0.82 | EPHX1 (0.43) | ITGB3SMN1; SMN2NOD1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051625-A1 | ASSESSING RISK FOR INTEGRIN ANTAGONIST/AGONIST MEDIATED DISEASES | Du Pont Pharmaceuticals Company (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999038014-A1 | ASSESSING RISK FOR INTEGRIN ANTAGONIST/AGONIST MEDIATED DISEASES | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-07-29 | — | — | WO | disclosed |