Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | PNMT | P11086 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25095004 | 0.80 | GABRA1 (0.35) | GABRA1GABRB2PNMT | |
| SCHEMBL8082902 | 0.76 | CTRC (0.39) | GABRA1GABRB2PNMTSLC6A2SLC6A4 | |
| SCHEMBL17449720 | 0.76 | PNMT (0.36) | GABRA1GABRB2PNMTSLC6A2CYP2D6 | |
| SCHEMBL8090789 | 0.75 | GABRA1 (0.52) | GABRA1GABRB2PNMTSLC6A2SLC6A4 | |
| SCHEMBL8097016 | 0.75 | CYP3A4 (0.35) | GABRA1GABRB2CYP3A4ALOX15ALOX12 | |
| SCHEMBL4337373 | 0.74 | PDCD1 (0.39) | PNMTSLC6A2SLC6A4CYP2D6SLC6A3 | |
| SCHEMBL900037 | 0.74 | ALDH1A1 (0.42) | PNMTSLC6A4CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL8094360 | 0.72 | ALOX5 (0.33) | PNMTSLC6A2SLC6A4CYP3A4ALOX15 | |
| SCHEMBL5018770 | 0.72 | PNMT (0.56) | GABRA1GABRB2PNMTSLC6A2SLC6A4 | |
| SCHEMBL20563034 | 0.71 | TAAR1 (0.53) | PNMTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053990-A2 | A method of producing an aromatic ketone and an aromatic ketone composition containing it | TORAY INDUSTRIES, INC. (JP) | 2000-11-22 | — | — | EP | disclosed |