Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081799 | 0.87 | GABRA1 (0.39) | PTGS2CA12CA1CA2CA4 | |
| SCHEMBL8088888 | 0.85 | ALDH1A1 (0.37) | NPC1RAB9ATP53POLBFAAH | |
| SCHEMBL6188780 | 0.81 | CA12 (0.41) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL8089505 | 0.81 | CA12 (0.38) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL7454339 | 0.81 | CA12 (0.38) | NPC1RAB9ATUBB1CA12CA1 | |
| SCHEMBL1274782 | 0.80 | CA1 (0.46) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL28621595 | 0.79 | ALDH1A1 (0.38) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL8092940 | 0.78 | NPC1 (0.36) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL2885322 | 0.78 | CA1 (0.50) | CA12CA1CA2CA4CA7 | |
| SCHEMBL2722296 | 0.77 | EGFR (0.38) | NPC1RAB9ACA2TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051394-A1 | POTASSIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037607-A1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 1999-07-29 | — | — | WO | disclosed |