Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | BCL2 | P10415 | 2/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093279 | 0.86 | CALM1 (0.50) | CALM1BCL2BCL2L1LMNALTA4H | |
| SCHEMBL7460513 | 0.85 | CALM1 (0.44) | TP53CALM1CYP1A2BCL2BCL2L1 | |
| SCHEMBL27884718 | 0.81 | LOXL2 (0.46) | CALM1CYP1A2CYP2A6KIF11BCL2 | |
| SCHEMBL311359 | 0.80 | TRPA1 (0.38) | TP53CYP1A2CYP2A6KIF11MAPT | |
| SCHEMBL2852601 | 0.79 | CALM1 (0.41) | TP53CALM1BCL2BCL2L1NPC1 | |
| SCHEMBL14989155 | 0.76 | SMN1; SMN2 (0.33) | CALM1CYP1A2NPC1ALDH1A1MAPK1 | |
| SCHEMBL6981018 | 0.76 | MAOB (0.42) | CALM1BCL2BCL2L1MAPTALDH1A1 | |
| SCHEMBL8602727 | 0.76 | ALOX5 (0.47) | CALM1BCL2BCL2L1SMN1; SMN2IDH1 | |
| SCHEMBL7014345 | 0.76 | CALM1 (0.41) | CALM1CYP1A2BCL2BCL2L1ALDH1A1 | |
| SCHEMBL16601111 | 0.76 | CALM1 (0.41) | CALM1BCL2BCL2L1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051394-A1 | POTASSIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037607-A1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 1999-07-29 | — | — | WO | disclosed |
| US-5294720-A | Viricides | THE DUPONT MERCK PHARMACEUTICAL CO. (US) | 1994-03-15 | — | — | US | disclosed |