Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105900 | 0.86 | AR (0.41) | CYP1A2CYP2D6CYP2C19ACACB | |
| SCHEMBL8099351 | 0.86 | RECQL (0.38) | CYP1A2CYP2D6CYP2C19ALDH1A1POLB | |
| SCHEMBL8105610 | 0.85 | CYP1A2 (0.41) | CYP1A2CYP2D6CYP2C19ALDH1A1LMNA | |
| SCHEMBL8096910 | 0.80 | CASP3 (0.37) | CYP1A2CYP2D6CYP2C19ALDH1A1LMNA | |
| SCHEMBL8098709 | 0.80 | TRPM8 (0.39) | — | |
| SCHEMBL8104045 | 0.78 | NPSR1 (0.46) | CYP1A2CYP2C19LMNAPOLBACACB | |
| SCHEMBL8099299 | 0.78 | USP2 (0.36) | CYP1A2CYP2D6CYP2C19ACACBCYP2C9 | |
| SCHEMBL8105285 | 0.74 | MAPT (0.37) | ALDH1A1POLBGAAMEN1KMT2A | |
| SCHEMBL6510492 | 0.74 | KAT2B (0.46) | CYP1A2CYP2D6CYP2C19ALDH1A1LMNA | |
| SCHEMBL8090534 | 0.73 | KAT2B (0.48) | CYP1A2CYP2D6CYP2C19ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |