Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | UGT8 | Q16880 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105719 | 0.87 | AR (0.42) | ARACACBNOTUMTAS1R3TAS1R1 | |
| SCHEMBL8090439 | 0.86 | CYP1A2 (0.53) | ACACBCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8098709 | 0.84 | TRPM8 (0.39) | — | |
| SCHEMBL8104045 | 0.83 | NPSR1 (0.46) | ACACBCYP1A2CYP2C19 | |
| SCHEMBL8099299 | 0.82 | USP2 (0.36) | ACACBCYP1A2CYP2D6CYP2C19UGT8 | |
| SCHEMBL8099351 | 0.80 | RECQL (0.38) | CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8096910 | 0.78 | CASP3 (0.37) | CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8097866 | 0.76 | NOTUM (0.41) | ARNOTUM | |
| SCHEMBL6511176 | 0.75 | AR (0.50) | ARNOTUMTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8096896 | 0.74 | AR (0.49) | ARNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |