Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098709 | 0.85 | TRPM8 (0.39) | — | |
| SCHEMBL8099351 | 0.84 | RECQL (0.38) | SMN1; SMN2GAAPOLBUSP2ALDH1A1 | |
| SCHEMBL8104045 | 0.84 | NPSR1 (0.46) | SMN1; SMN2POLBMAPTCYP1A2TSHR | |
| SCHEMBL8097540 | 0.82 | POLB (0.36) | CASP3HPGDSMN1; SMN2GAAPOLB | |
| SCHEMBL8099299 | 0.80 | USP2 (0.36) | USP2CYP1A2CYP2D6CYP2C9CYP3A4 | |
| SCHEMBL8090439 | 0.80 | CYP1A2 (0.53) | HPGDGAAPOLBUSP2ALDH1A1 | |
| SCHEMBL8105900 | 0.78 | AR (0.41) | CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8107067 | 0.78 | ACACB (0.47) | SMN1; SMN2GAAATML3MBTL1POLB | |
| SCHEMBL8099572 | 0.78 | ACACB (0.47) | SMN1; SMN2GAAATML3MBTL1POLB | |
| SCHEMBL8090426 | 0.74 | LMNA (0.40) | SMN1; SMN2GAAALDH1A1MAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |