Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103660 | 0.89 | NOTUM (0.45) | PIM1PIM2HCRTR1HCRTR2NOTUM | |
| SCHEMBL8097093 | 0.85 | PIM1 (0.41) | PIM1PIM2HCRTR1HCRTR2EPHX2 | |
| SCHEMBL8089994 | 0.79 | MGLL (0.45) | MAPTDRD2DRD3LMNAPOLB | |
| SCHEMBL8098686 | 0.78 | THRB (0.46) | MAPT | |
| SCHEMBL5827269 | 0.78 | MEN1 (0.43) | ALDH1A1NOTUMDRD2DRD3POLB | |
| SCHEMBL8098677 | 0.78 | MAPT (0.38) | PIM1PIM2HCRTR1HCRTR2EPHX2 | |
| SCHEMBL8103211 | 0.76 | FADS1 (0.44) | ALDH1A1MAPTDRD2DRD3LMNA | |
| SCHEMBL8552157 | 0.76 | DRD2 (0.44) | PIM1PIM2HCRTR1HCRTR2NOTUM | |
| SCHEMBL8103729 | 0.76 | PIM1 (0.44) | PIM1PIM2HCRTR1HCRTR2EPHX2 | |
| SCHEMBL8090389 | 0.74 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |