Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 8/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105616 | 0.96 | PPARG (0.40) | SMN1; SMN2PPARGSCN9ASCN5AMEN1 | |
| SCHEMBL8099518 | 0.96 | PPARG (0.40) | SMN1; SMN2PPARGSCN9ASCN5AMEN1 | |
| SCHEMBL8098997 | 0.90 | PPARG (0.45) | PPARGMEN1KMT2A | |
| SCHEMBL8767779 | 0.90 | GABRA5 (0.39) | PPARGSCN9AGABRA5SCN5ACCR4 | |
| SCHEMBL8099435 | 0.88 | GABRA5 (0.36) | SMN1; SMN2PPARGSCN9AGABRA5SCN5A | |
| SCHEMBL8874498 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2SCN9AGABRA5MEN1KMT2A | |
| SCHEMBL8766955 | 0.86 | MGLL (0.39) | PPARGSCN9A | |
| SCHEMBL8767147 | 0.86 | MGLL (0.39) | PPARGSCN9A | |
| SCHEMBL8090051 | 0.85 | P4HTM (0.45) | SMN1; SMN2SCN9ASCN5AMEN1KMT2A | |
| SCHEMBL8875618 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2PPARGGABRA5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673932-B1 | Sulfonamidocarbonyl-pyridine-2-carboxamides as well as their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AG (DE) | 2000-06-07 | — | — | EP | disclosed |
| EP-0673932-A1 | Sulfonamidocarbonyl-pyridine-2-carboxamides as well as their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-27 | — | — | EP | disclosed |