Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 12/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233299 | 0.91 | GABRA5 (0.37) | GABRA5PPARGSCN9ASCN5A | |
| SCHEMBL8874638 | 0.88 | GABRA5 (0.38) | GABRA5PPARGSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8090622 | 0.88 | SMN1; SMN2 (0.39) | GABRA5PPARGSCN9ASCN5ASMN1; SMN2 | |
| SCHEMBL8105616 | 0.84 | PPARG (0.40) | PPARGSCN9ASCN5ASMN1; SMN2 | |
| SCHEMBL8099518 | 0.84 | PPARG (0.40) | PPARGSCN9ASCN5ASMN1; SMN2 | |
| SCHEMBL8098997 | 0.80 | PPARG (0.45) | PPARG | |
| SCHEMBL8916805 | 0.78 | GABRA5 (0.39) | GABRA5PPARGSMN1; SMN2ALDH1A1 | |
| SCHEMBL8767779 | 0.78 | GABRA5 (0.39) | GABRA5PPARGSCN9ASCN5A | |
| SCHEMBL8874498 | 0.77 | SMN1; SMN2 (0.44) | GABRA5SCN9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8767147 | 0.74 | MGLL (0.39) | PPARGSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673932-B1 | Sulfonamidocarbonyl-pyridine-2-carboxamides as well as their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AG (DE) | 2000-06-07 | — | — | EP | disclosed |
| EP-0673932-A1 | Sulfonamidocarbonyl-pyridine-2-carboxamides as well as their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-27 | — | — | EP | disclosed |