SCHEMBL8090731

SCHEMBL8090731

O=C(c1ccc(-c2ccc(O)cc2)c(O)c1)c1ccc(-c2ccc(O)cc2)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 1/20 0.61
MMP3 P08254 1/20 0.61
LMNA P02545 2/20 0.56
MAPT P10636 2/20 0.56
HTT P42858 2/20 0.56
ESR1 P03372 1/20 0.56
ESR2 Q92731 1/20 0.56
PKM P14618 1/20 0.56
HPGD P15428 1/20 0.56
HSD17B1 P14061 4/20 0.54
HSD17B2 P37059 2/20 0.54
MEN1 O00255 1/20 0.53
RAB9A P51151 1/20 0.53
KMT2A Q03164 1/20 0.53
CNR2 P34972 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HSD17B10 Q99714 1/20 0.50
POLB P06746 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27271938 0.91 MEN1 (0.70) MMP2MMP3LMNAMAPTHTT
SCHEMBL28211489 0.86 HSD17B10 (0.58) MMP2MMP3LMNAMAPTESR2
SCHEMBL13589367 0.84 MMP2 (0.68) MMP2MMP3LMNAMAPTHTT
SCHEMBL26981142 0.78 KDM4E (0.64) LMNAMAPTHTTHPGDSMN1; SMN2
SCHEMBL5476111 0.78 MAPT (0.68) MMP2MMP3LMNAMAPTHTT
SCHEMBL5652175 0.78 ALOX5 (0.61) LMNAMAPTESR2HSD17B1HSD17B10
SCHEMBL27271189 0.77 VCAM1 (0.54) MMP2MMP3LMNAMAPTHTT
SCHEMBL4671519 0.77 ESR1 (0.83) MMP2MMP3LMNAMAPTHTT
SCHEMBL10535107 0.77 ESR1 (0.83) MMP2MMP3LMNAMAPTHTT
SCHEMBL11043579 0.77 ESR1 (0.83) MMP2MMP3LMNAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0637613-B1 RESIN COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2000-10-25 EP disclosed
US-5543474-A BLEND OF A AROMATIC POLYAMIDEIMIDE COPOLYMER AND A POLYESTER MITSUBISHI GAS COMPANY, INC. (JP) 1996-08-06 US disclosed
EP-0637613-A1 RESIN COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1995-02-08 EP disclosed