Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7834401 | 0.92 | TBXAS1 (0.36) | TBXAS1ALDH1A1HPGDGAAMAPT | |
| SCHEMBL8880656 | 0.87 | METAP1 (0.38) | ALDH1A1HPGDGAAMAPTHSD17B10 | |
| SCHEMBL8880066 | 0.85 | HRH1 (0.43) | ALDH1A1MAPTMEN1KMT2AADORA3 | |
| SCHEMBL8881385 | 0.85 | GABRG2 (0.41) | ALDH1A1HPGDGAAMAPTHSD17B10 | |
| SCHEMBL8880563 | 0.85 | GABRG2 (0.38) | ALDH1A1HPGDGAAMAPTHSD17B10 | |
| SCHEMBL8097517 | 0.84 | KMT2A (0.43) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL8090657 | 0.84 | GABRA1 (0.33) | ALDH1A1HPGDGAAMAPTHSD17B10 | |
| SCHEMBL8881176 | 0.84 | CYP19A1 (0.43) | ALDH1A1MAPTHSD17B10KDM4EMEN1 | |
| SCHEMBL8317441 | 0.83 | GABRA1 (0.41) | ALDH1A1HPGDGAAMAPTHSD17B10 | |
| SCHEMBL8879965 | 0.83 | MAPT (0.46) | ALDH1A1HPGDGAAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057454-A | USEFUL FOR TREATING OR PREVENTING ALL ISCHAEMIAS (SUCH AS FOCAL OR GLOBAL ISCHAEMIA) RESULTING FROM CEREBROVASCULAR DISORDERS | RHONE-POULENC RORER S.A. (FR) | 2000-05-02 | — | — | US | disclosed |
| US-5902803-A | 5H,10H-imidazo 1,2-a!indeno 1,2-e!pyrazin-4-one derivatives, preparation thereof, and drugs containing said derivatives | RHONE-POULENC RORER S.A. (FR) | 1999-05-11 | — | — | US | disclosed |