Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847087 | 0.87 | KMT2A (0.43) | KMT2AAPOBEC3AAPOBEC3GMEN1ALDH1A1 | |
| SCHEMBL8879965 | 0.85 | MAPT (0.46) | KMT2ALMNAMEN1ALDH1A1HPGD | |
| SCHEMBL8091069 | 0.84 | TBXAS1 (0.36) | KMT2AMEN1ALDH1A1HPGDGABRA1 | |
| SCHEMBL8880656 | 0.83 | METAP1 (0.38) | KMT2ALMNAMEN1ALDH1A1HPGD | |
| SCHEMBL8880066 | 0.81 | HRH1 (0.43) | KMT2ALMNAMEN1ALDH1A1GABRA1 | |
| SCHEMBL8880563 | 0.81 | GABRG2 (0.38) | KMT2ALMNAMEN1ALDH1A1HPGD | |
| SCHEMBL8881385 | 0.81 | GABRG2 (0.41) | KMT2ALMNAMEN1ALDH1A1HPGD | |
| SCHEMBL8090657 | 0.81 | GABRA1 (0.33) | KMT2AMEN1ALDH1A1HPGDGABRA1 | |
| SCHEMBL8881176 | 0.81 | CYP19A1 (0.43) | KMT2ALMNAMEN1ALDH1A1GABRA1 | |
| SCHEMBL8683083 | 0.80 | SMN1; SMN2 (0.37) | LMNAALDH1A1HPGDTRPC5HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057454-A | USEFUL FOR TREATING OR PREVENTING ALL ISCHAEMIAS (SUCH AS FOCAL OR GLOBAL ISCHAEMIA) RESULTING FROM CEREBROVASCULAR DISORDERS | RHONE-POULENC RORER S.A. (FR) | 2000-05-02 | — | — | US | disclosed |
| US-5902803-A | 5H,10H-imidazo 1,2-a!indeno 1,2-e!pyrazin-4-one derivatives, preparation thereof, and drugs containing said derivatives | RHONE-POULENC RORER S.A. (FR) | 1999-05-11 | — | — | US | disclosed |