Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083332 | 0.87 | KIF11 (0.35) | ALDH1A1MAPTALOX12SMN1; SMN2KDM4E | |
| SCHEMBL8090988 | 0.87 | MTOR (0.44) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8091208 | 0.85 | PIK3CD (0.44) | ALDH1A1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL8089937 | 0.83 | KIF11 (0.39) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8099890 | 0.80 | GHSR (0.39) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8100086 | 0.77 | PIK3CD (0.53) | ALDH1A1MAPTLMNAALOX12HTT | |
| SCHEMBL8095224 | 0.77 | PIK3CD (0.34) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8099045 | 0.77 | MAPT (0.39) | ALDH1A1MAPTLMNAALOX12HTT | |
| SCHEMBL8091600 | 0.76 | PIK3CA (0.40) | PIK3CAPIK3CD | |
| SCHEMBL8083982 | 0.76 | PIK3CD (0.34) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007748-A2 | TRISUBSTITUTED PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF PROLIFERATIVE DISEASES | ASTRAZENECA AB (SE) | 2009-01-15 | — | — | WO | disclosed |