SCHEMBL8091434

SCHEMBL8091434

COC12CCC(c3ccc(CC(=O)N[CH]CCCN)cc3)(CC1)CC2

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 2/20 0.31
CCR1 P32246 1/20 0.30
LOXL2 Q9Y4K0 1/20 0.30
AOC3 Q16853 1/20 0.30
ADRA1D P25100 1/20 0.30
ADRA1A P35348 1/20 0.30
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8091469 0.86 ADRA1D (0.33) ALDH1A1KMT2AADRA1DADRA1A
SCHEMBL8091664 0.84 POLB (0.33) ALDH1A1CCR1LOXL2
SCHEMBL8095325 0.81 POLB (0.33) ALDH1A1
SCHEMBL8098021 0.76 ITGB3 (0.33) ALDH1A1HTTKMT2ACCR1
SCHEMBL8098032 0.75 ITGB3 (0.32) ALDH1A1HTTKMT2ACCR1
SCHEMBL9248972 0.74 CA2 (0.42) ALDH1A1HTT
SCHEMBL8091474 0.73 ADRA1D (0.40) KMT2AADRA1DADRA1A
SCHEMBL8091436 0.73
SCHEMBL8098109 0.72 ALDH1A1 (0.33) ALDH1A1
SCHEMBL8091620 0.70 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0792883-B1 Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 2000-12-20 EP disclosed
EP-0792883-A1 Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1997-09-03 EP disclosed