Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091474 | 0.88 | ADRA1D (0.40) | ADRA1DADRA1AKMT2AHPGDL3MBTL1 | |
| SCHEMBL8090129 | 0.86 | ALDH1A1 (0.34) | ALDH1A1RAB9A | |
| SCHEMBL8091434 | 0.86 | ALDH1A1 (0.32) | ADRA1DADRA1AKMT2AALDH1A1 | |
| SCHEMBL8091412 | 0.83 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL8090106 | 0.79 | ITGB3 (0.37) | ADRA1DADRA1AKMT2AITGB3ITGA2B | |
| SCHEMBL8091473 | 0.77 | — | — | |
| SCHEMBL8090137 | 0.77 | NPC1 (0.45) | KMT2AALDH1A1HPGDITGB3ITGA2B | |
| SCHEMBL8091494 | 0.77 | SPHK1 (0.34) | ALDH1A1HPGDRAB9A | |
| SCHEMBL8090161 | 0.73 | SPHK1 (0.33) | — | |
| SCHEMBL8083447 | 0.72 | SPHK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |