Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 5/20 | 0.35 |
| ▸ | MC5R | P33032 | 3/20 | 0.35 |
| ▸ | MC3R | P41968 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | MC1R | Q01726 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098096 | 0.90 | CES2 (0.35) | CES2MC4RMC3RMAPTHTT | |
| SCHEMBL8091511 | 0.77 | SMN1; SMN2 (0.40) | LMNAALDH1A1POLB | |
| SCHEMBL8091583 | 0.66 | MC4R (0.39) | MC4RMC5RMC3RMC1R | |
| SCHEMBL8091588 | 0.66 | MC4R (0.38) | MC4RMC5RMC3RMC1R | |
| SCHEMBL7439957 | 0.66 | HCAR2 (0.47) | CES2MAPTHTTLMNARXFP1 | |
| SCHEMBL8095466 | 0.64 | CYP2C19 (0.39) | CYP1A2KDM4EALDH1A1 | |
| SCHEMBL8095467 | 0.64 | CYP3A4 (0.38) | CYP1A2KDM4EALDH1A1 | |
| SCHEMBL8090157 | 0.63 | MTNR1A (0.41) | LMNAALDH1A1POLB | |
| SCHEMBL8095266 | 0.62 | MMP1 (0.39) | CYP1A2KDM4E | |
| SCHEMBL31617869 | 0.62 | MC4R (0.73) | MC4RMC5RMC3RMC1RCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |