Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | MMP2 | P08253 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090096 | 0.90 | TPSAB1 (0.36) | CAPN1USP2TPSAB1EPHX2TBXA2R | |
| SCHEMBL8098096 | 0.81 | CES2 (0.35) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL8091691 | 0.79 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8091511 | 0.78 | SMN1; SMN2 (0.40) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL7444776 | 0.73 | CAPN1 (0.35) | CAPN1USP2TPSAB1EPHX2TBXA2R | |
| SCHEMBL8091477 | 0.71 | TBXA2R (0.40) | CAPN1USP2TPSAB1EPHX2TBXA2R | |
| SCHEMBL8098063 | 0.70 | CES2 (0.37) | ALDH1A1KDM4ELMNAPKM | |
| SCHEMBL7444786 | 0.70 | ALDH1A1 (0.34) | CAPN1USP2EPHX2TBXA2RALDH1A1 | |
| SCHEMBL8095300 | 0.67 | CYP3A4 (0.36) | ALDH1A1 | |
| SCHEMBL7445495 | 0.67 | USP2 (0.32) | USP2TPSAB1TBXA2RALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |