Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093558 | 0.80 | CYP19A1 (0.37) | — | |
| Fumaric Acid SCHEMBL8091527 | 0.74 | HRH3 (0.35) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Fumaric Acid SCHEMBL8091522 | 0.74 | HRH3 (0.35) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8097510 | 0.72 | ADRA2A (0.47) | — | |
| SCHEMBL6951243 | 0.70 | ADRA2A (0.38) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8092589 | 0.64 | ADRA2A (0.47) | — | |
| SCHEMBL11195819 | 0.63 | ATM (0.44) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8097775 | 0.63 | ACHE (0.38) | HTR1AHTR2AHTR2B | |
| SCHEMBL8091875 | 0.62 | ADRA2A (0.43) | HTR1AHTR2AHRH1HTR2B | |
| SCHEMBL8085006 | 0.62 | ADRA2A (0.43) | HTR1AHTR2AHRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |