Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CCR3 | P51677 | 12/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084693 | 0.87 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL8091525 | 0.80 | HDAC3 (0.35) | — | |
| SCHEMBL8093566 | 0.78 | ADRA2A (0.46) | CCR3 | |
| SCHEMBL8097510 | 0.74 | ADRA2A (0.47) | — | |
| SCHEMBL8092912 | 0.72 | SLC6A4 (0.35) | CYP19A1SLC6A4MCHR1 | |
| Fumaric Acid SCHEMBL8093561 | 0.72 | CCR3 (0.37) | CYP19A1SLC6A2SLC6A4SLC6A3KCNH2 | |
| Fumaric Acid SCHEMBL8093552 | 0.72 | CCR3 (0.37) | CYP19A1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL6957391 | 0.68 | SLC6A2 (0.39) | CYP19A1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL8092589 | 0.66 | ADRA2A (0.47) | — | |
| SCHEMBL8097775 | 0.65 | ACHE (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |