Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097409 | 0.86 | CYP19A1 (0.40) | CYP19A1HTR1AMCHR1 | |
| Fumaric Acid SCHEMBL8092908 | 0.74 | SLC6A4 (0.38) | SLC6A4ADRA2AADRA2BADRA2CPRMT5 | |
| Fumaric Acid SCHEMBL8092913 | 0.74 | SLC6A4 (0.38) | SLC6A4ADRA2AADRA2BADRA2CPRMT5 | |
| SCHEMBL6950989 | 0.71 | SLC6A4 (0.45) | SLC6A4ADRA2AADRA2BADRA2CCYP19A1 | |
| SCHEMBL8091525 | 0.70 | HDAC3 (0.35) | HTR1AHTR2AHTR2BHDAC8HDAC6 | |
| SCHEMBL9635389 | 0.66 | SLC6A4 (0.44) | SLC6A4ADRA2AADRA2BADRA2CCYP19A1 | |
| SCHEMBL8085006 | 0.66 | ADRA2A (0.43) | SLC6A4ADRA2ACYP19A1HTR1ADRD2 | |
| SCHEMBL8091875 | 0.66 | ADRA2A (0.43) | SLC6A4ADRA2ACYP19A1HTR1ADRD2 | |
| SCHEMBL8093366 | 0.65 | ADRA2A (0.33) | ADRA2A | |
| SCHEMBL8090880 | 0.65 | MCHR1 (0.32) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127396-A | Imidazoline compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |