Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10269089 | 0.87 | CSNK2A1 (0.47) | TP53BCL2BCL2L1LMNAALOX5 | |
| SCHEMBL11089774 | 0.86 | LMNA (0.52) | TP53BCL2BCL2L1LMNAALOX5 | |
| SCHEMBL9487860 | 0.85 | TRPA1 (0.44) | TP53LMNACYP1A2CYP2A6NPC1 | |
| SCHEMBL8094436 | 0.84 | LMNA (0.50) | TP53BCL2BCL2L1LMNAALOX5 | |
| SCHEMBL9066731 | 0.84 | BCL2 (0.50) | TP53BCL2BCL2L1ALDH1A1ALOX5 | |
| SCHEMBL8086923 | 0.81 | CALM1 (0.55) | TP53BCL2BCL2L1LMNAL3MBTL1 | |
| SCHEMBL4517872 | 0.81 | MEN1 (0.61) | TP53BCL2BCL2L1MAPTALOX5 | |
| SCHEMBL10454618 | 0.81 | TP53 (0.46) | TP53BCL2BCL2L1LMNACYP1A2 | |
| SCHEMBL6548117 | 0.81 | HTR2A (0.56) | TP53BCL2BCL2L1LMNAL3MBTL1 | |
| SCHEMBL444673 | 0.80 | TRPA1 (0.48) | TP53LMNACYP1A2CYP2A6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |