Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6548117 | 0.95 | HTR2A (0.56) | CALM1HTR2ATP53LMNABCL2 | |
| SCHEMBL11205678 | 0.93 | HTR2A (0.54) | CALM1HTR2ATP53LMNABCL2 | |
| SCHEMBL8093837 | 0.93 | SLC6A4 (0.47) | CALM1HTR2ATP53LMNABCL2 | |
| SCHEMBL8094436 | 0.85 | LMNA (0.50) | CALM1HTR2ATP53LMNALTA4H | |
| SCHEMBL8096061 | 0.85 | LTA4H (0.46) | LTA4HL3MBTL1TSHRSLC6A2SLC6A4 | |
| SCHEMBL8095786 | 0.84 | LTA4H (0.46) | HTR2ALTA4HSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6547993 | 0.84 | POLB (0.45) | HTR2ALMNAL3MBTL1TSHRSLC6A2 | |
| SCHEMBL11089774 | 0.83 | LMNA (0.52) | CALM1TP53LMNALTA4HPLA2G10 | |
| SCHEMBL27473436 | 0.83 | LMNA (0.44) | HTR2ATP53LMNASLC6A2SLC6A4 | |
| SCHEMBL11299196 | 0.83 | SLC6A2 (0.44) | TP53LMNASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |