Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097712 | 0.92 | KMT2A (0.39) | CA2KMT2AMEN1MTORPIK3CA | |
| SCHEMBL8091073 | 0.90 | KMT2A (0.37) | CA2KMT2AMTORPIK3CAPIK3CG | |
| SCHEMBL8083973 | 0.88 | ALDH1A1 (0.43) | CA2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8089917 | 0.87 | PIK3CA (0.39) | CA2KMT2AMTORPIK3CAPIK3CG | |
| SCHEMBL8092637 | 0.86 | KMT2A (0.42) | CA2KMT2AMTORPIK3CAPIK3CG | |
| SCHEMBL8097257 | 0.86 | ALDH1A1 (0.41) | CA2KMT2AMEN1LMNARAB9A | |
| SCHEMBL8090246 | 0.85 | PIK3CA (0.42) | KMT2AMEN1HTTMAPTMTOR | |
| SCHEMBL8090158 | 0.84 | MTOR (0.46) | CA2MTORPIK3CAPIK3CGCA12 | |
| SCHEMBL8099749 | 0.84 | MTOR (0.40) | KMT2AMTORPIK3CAPIK3CG | |
| SCHEMBL8094619 | 0.83 | PIP4K2A (0.40) | KMT2AMTORPIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007748-A2 | TRISUBSTITUTED PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF PROLIFERATIVE DISEASES | ASTRAZENECA AB (SE) | 2009-01-15 | — | — | WO | disclosed |