Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16993653 | 0.82 | AIP (0.44) | POLBALDH1A1MAPTLMNAGRIN2C | |
| SCHEMBL8304526 | 0.75 | POLB (0.52) | POLBRECQLABCC1ALDH1A1MAPT | |
| SCHEMBL7217363 | 0.74 | TSHR (0.41) | ABCC1ALDH1A1MAPTNPC1HPGD | |
| SCHEMBL3228565 | 0.70 | POLB (0.47) | POLBRECQLABCC1ALDH1A1MAPT | |
| SCHEMBL3497284 | 0.70 | ALDH1A1 (0.61) | POLBRECQLABCC1ALDH1A1MAPT | |
| SCHEMBL5080674 | 0.66 | DAO (0.42) | POLBRECQLABCC1ALDH1A1MAPT | |
| SCHEMBL8330157 | 0.64 | PRNP (0.45) | ABCC1ALDH1A1LMNAL3MBTL1RAB9A | |
| SCHEMBL21612947 | 0.64 | ALDH1A1 (0.61) | POLBABCC1ALDH1A1MAPTLMNA | |
| SCHEMBL8306201 | 0.64 | L3MBTL1 (0.42) | POLBRECQLABCC1ALDH1A1MAPT | |
| SCHEMBL13398540 | 0.63 | GRM6 (0.49) | POLBRECQLALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797578-B1 | FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO CO (US) | 2000-05-10 | — | — | EP | disclosed |
| CN-1052234-C | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2000-05-10 | — | — | CN | disclosed |
| CN-1176642-A | Fungicide for preventing and treating take-all disease of plant | MONSANTO CO (US) | 1998-03-18 | — | — | CN | disclosed |
| EP-0797578-A1 | FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO COMPANY (US) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018631-A1 | FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO COMPANY (US) | 1996-06-20 | — | — | WO | disclosed |
| US-5486621-A | 4,5-DOMETHYL-N-2-PROPENYL-2-(TRIMETHYLSILYL)-3-THIOPHENE CARBOXAMIDE | MONSANTO COMPANY (US) | 1996-01-23 | — | — | US | disclosed |