Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089236 | 0.85 | SMN1; SMN2 (0.38) | NPC1RAB9AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL8089421 | 0.84 | ALDH1A1 (0.40) | NPC1RAB9AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL10909436 | 0.84 | RXRA (0.44) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8090802 | 0.82 | MAPT (0.36) | KDM4EL3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10015983 | 0.81 | NPC1 (0.45) | NPC1RAB9AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL8090599 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KDM4EL3MBTL1P2RX7MEN1 | |
| SCHEMBL14729157 | 0.78 | NPC1 (0.46) | NPC1RAB9AALDH1A1SMN1; SMN2P2RX7 | |
| SCHEMBL10911390 | 0.76 | NLRP3 (0.44) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL8094219 | 0.73 | L3MBTL1 (0.42) | NPC1RAB9AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL13091046 | 0.73 | NPC1 (0.43) | NPC1RAB9AALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150304-A | HERBICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-11-21 | — | — | US | disclosed |
| US-5840661-A | HERBICIDES OR INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | disclosed |