Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097595 | 0.88 | KMT2A (0.37) | SMN1; SMN2ATMALDH1A1KMT2ACASP3 | |
| SCHEMBL8105978 | 0.88 | TP53 (0.42) | LMNAPOLBTP53MAPTALDH1A1 | |
| SCHEMBL8105911 | 0.87 | KMT2A (0.35) | LMNAPOLBTP53MAPTKDM4E | |
| SCHEMBL8097540 | 0.87 | POLB (0.36) | POLBTP53MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8105898 | 0.84 | EPHX2 (0.35) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8103628 | 0.82 | SLC6A4 (0.37) | MAPTKDM4ESMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL8105889 | 0.81 | CACNA1H (0.35) | ALDH1A1CYP2D6 | |
| SCHEMBL8105285 | 0.80 | MAPT (0.37) | POLBMAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8102959 | 0.80 | SMN1; SMN2 (0.38) | LMNAMAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8098460 | 0.80 | NTMT1 (0.35) | TP53MAPTKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |