Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6548002 | 0.91 | TAAR1 (0.46) | TAAR1PTGS1PTGS2ARKMT2A | |
| SCHEMBL11210876 | 0.91 | TAAR1 (0.46) | TAAR1PTGS1PTGS2ARKMT2A | |
| SCHEMBL8093837 | 0.91 | SLC6A4 (0.47) | SLC6A2SLC6A4SLC6A3HTR2AKEAP1 | |
| SCHEMBL8095627 | 0.89 | LTA4H (0.53) | LTA4HTAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6547993 | 0.87 | POLB (0.45) | SLC6A2SLC6A4SLC6A3POLBHTR2A | |
| SCHEMBL8099386 | 0.85 | HTR2A (0.42) | LTA4HSLC6A2SLC6A4SLC6A3FFAR1 | |
| SCHEMBL8086923 | 0.84 | CALM1 (0.55) | LTA4HSLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL8100277 | 0.84 | DHFR (0.43) | LTA4HTAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6548117 | 0.84 | HTR2A (0.56) | HTR2A | |
| SCHEMBL11028810 | 0.84 | TAAR1 (0.52) | TAAR1PTGS1PTGS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |