SCHEMBL810047

SCHEMBL810047

CC(=O)CCCCCOc1ccc(OCCOCC(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PLA2G4B P0C869 5/20 0.56
GAA P10253 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.47
HDAC1 Q13547 5/20 0.47
HDAC2 Q92769 5/20 0.47
PPARA Q07869 2/20 0.47
HDAC3 O15379 3/20 0.46
HDAC4 P56524 3/20 0.46
HDAC7 Q8WUI4 3/20 0.46
HDAC10 Q969S8 3/20 0.46
HDAC11 Q96DB2 3/20 0.46
HDAC8 Q9BY41 3/20 0.46
HDAC6 Q9UBN7 3/20 0.46
HDAC9 Q9UKV0 3/20 0.46
HDAC5 Q9UQL6 3/20 0.46
TP53 P04637 1/20 0.45
TSHR P16473 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809958 0.89 PLA2G4B (0.56) PLA2G4BGAAL3MBTL1
SCHEMBL810001 0.85 CYSLTR2 (0.43) PLA2G4B
SCHEMBL2116281 0.83 ALOX15 (0.54) PLA2G4BL3MBTL1HDAC1HDAC2
SCHEMBL3438976 0.82 CES2 (0.50) PLA2G4BGAATSHR
SCHEMBL12160420 0.82 CES2 (0.53) PLA2G4BPPARAHDAC11TSHR
SCHEMBL26343047 0.81 GAA (0.56) GAAL3MBTL1HDAC1HDAC2HDAC3
SCHEMBL13418125 0.81 ALOX15 (0.53) PLA2G4BL3MBTL1TSHR
SCHEMBL10361085 0.80 HDAC1 (0.65) GAAL3MBTL1HDAC1HDAC2PPARA
SCHEMBL809992 0.80 ALOX15 (0.61) PLA2G4BL3MBTL1TSHR
SCHEMBL17947680 0.80 GAA (0.75) PLA2G4BGAAL3MBTL1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7902319-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2011-03-08 US disclosed
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-05-06 US disclosed
US-7671168-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2010-03-02 US disclosed
US-20070141113-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM DDT, ACMSD, HPD PLA2G4B 4319/4885GAA 2081/4885L3MBTL1 4852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.