Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNG | P07510 | 1/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6048041 | 0.79 | HMOX1 (0.40) | — | |
| SCHEMBL11206802 | 0.71 | MAPK1 (0.43) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11203232 | 0.69 | ABCB11 (0.41) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11208529 | 0.68 | HDAC3 (0.43) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11264433 | 0.68 | LMNA (0.68) | LMNAMEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL11360364 | 0.67 | KCNH2 (0.43) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22728705 | 0.67 | NAAA (0.39) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11269019 | 0.67 | ABCB11 (0.48) | NAAAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11639984 | 0.66 | TAAR1 (0.42) | — | |
| Clomoxir SCHEMBL112980 | 0.66 | ABCB11 (0.47) | NAAAHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000159766-A | PRODUCTION OF IMIDAZOLE DERIVATIVE | UBE IND LTD | 2000-06-13 | — | — | JP | disclosed |