Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8116316 | 0.79 | HTT (0.44) | CA2LMNAMAPK1HTTRAB9A | |
| SCHEMBL3126876 | 0.78 | MRGPRX4 (0.51) | LMNAMAPK1HTTRAB9APOLB | |
| SCHEMBL31401479 | 0.77 | TSHR (0.42) | APEX1RARBNR1H4KDM4EHSD17B10 | |
| SCHEMBL11770021 | 0.76 | RAB9A (0.56) | HTTRAB9AAPEX1KDM4EHSD17B10 | |
| SCHEMBL11828338 | 0.76 | ALDH1A1 (0.52) | LMNAMAPK1HTTRAB9AKDM4E | |
| SCHEMBL8402587 | 0.75 | LMNA (0.53) | CA2LMNAMAPK1HTTRAB9A | |
| SCHEMBL2001981 | 0.75 | APEX1 (0.72) | CA2LMNAAPEX1MAPTTSHR | |
| SCHEMBL25465991 | 0.71 | ALDH1A1 (0.47) | LMNAMAPK1HTTRAB9AKDM4E | |
| SCHEMBL14516636 | 0.71 | KCNQ3 (0.52) | CA2LMNAMAPK1HTTRAB9A | |
| SCHEMBL1018288 | 0.71 | CA2 (0.52) | CA2HTTRAB9AKDM4ECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031572-A1 | PYRIDYLPYRROLE DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-30 | — | — | EP | disclosed |