Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100163 | 0.86 | PKM (0.44) | MEN1KMT2AFLT3KDM4EALDH1A1 | |
| SCHEMBL7920472 | 0.81 | DCTPP1 (0.48) | KDM4EALDH1A1HPGDIDH1GAA | |
| SCHEMBL8092506 | 0.79 | ALDH1A1 (0.55) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL16805033 | 0.78 | MEN1 (0.50) | MEN1KMT2AFLT3KDM4EALDH1A1 | |
| SCHEMBL8106201 | 0.77 | CTRC (0.45) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL8099799 | 0.77 | NPC1 (0.51) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL8101985 | 0.76 | GRIN1 (0.46) | MEN1KMT2AFLT3KDM4EALDH1A1 | |
| SCHEMBL8108277 | 0.75 | RAD51 (0.55) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL8102203 | 0.72 | HSP90AA1 (0.47) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL8100020 | 0.71 | RAD51 (0.49) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071930-A | FOR INHIBITION OF MITOSIS OR TUMOR GROWTH | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-06-06 | — | — | US | disclosed |
| US-5994367-A | PREVENT CELL MITOSIS; ANTICARCINOGENIC AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1999-11-30 | — | — | US | disclosed |