Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.64 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 7/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109656 | 0.86 | OPRM1 (0.68) | OPRM1OPRK1OPRL1SLC6A4HSD11B1 | |
| SCHEMBL8103996 | 0.82 | OPRM1 (0.74) | OPRM1OPRK1OPRL1SLC6A4HSD11B1 | |
| Formic Acid SCHEMBL27577042 | 0.81 | OPRM1 (0.61) | OPRM1OPRK1OPRL1SLC6A4HSD11B1 | |
| SCHEMBL4673535 | 0.81 | OPRM1 (0.56) | OPRM1OPRK1OPRL1SLC6A4HSD11B1 | |
| SCHEMBL4673580 | 0.80 | HTR1B (0.71) | OPRM1OPRK1OPRL1SLC6A4HTR1A | |
| Hydrochloric Acid SCHEMBL7255624 | 0.80 | ADRA1D (0.83) | OPRM1OPRK1OPRL1SLC6A4ADRA1D | |
| Bicarbonate SCHEMBL7460768 | 0.79 | HSD11B1 (0.65) | OPRM1OPRK1OPRL1SLC6A4HSD11B1 | |
| SCHEMBL5340537 | 0.79 | HSD11B1 (0.68) | OPRM1OPRK1OPRL1SLC6A4HSD11B1 | |
| SCHEMBL14280674 | 0.78 | OPRL1 (1.00) | OPRM1OPRK1OPRL1SLC6A4HSD11B1 | |
| SCHEMBL18324763 | 0.78 | KDM4E (0.69) | OPRM1OPRK1OPRL1SLC6A4HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5998412-A | ANTIARTHRITIC AGENTS; OSTEOPOROSIS | SYNTEX (U.S.A.) INC. (US) | 1999-12-07 | — | — | US | disclosed |